|
|
Featured Article
Featured Podcast
|
Medical Word of the Day
|
07/30/2010 12:00 AM
|
|
Favism
|
|
Favism: A condition characterized by hemolytic anemia
(breakup of red blood cells) after eating fava beans (Vicia fava) or being exposed to the
pollen of the fava plant. This dangerous reaction occurs exclusively in people with a
deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), an X-linked genetic
trait. However, not all G6PD-deficient families appear at risk for favism, indicating the
additional need for a single autosomal (not X-linked) gene to create the susceptibility to
favism of G6PD-deficient persons. The active hemolytic principle in fava beans is >
likely DOPA-quinone. Differences in susceptibility to favism may be related to differences
in the enzymatic system that converts L-DOPA to DOPA-quinone.
MedTerms (TM) is the Medical Dictionary of MedicineNet.com. We Bring Doctors' Knowledge To You
|
|
|
 |